Genetic variants associated with longitudinal changes in brain structure across the lifespan

Área de publicación Neurociencia Cognitiva
Tipo de publicación Articles
Lugar de publicación Nature Neuroscience
Fecha de publicación 2022
Autores Hieab Adams - Brouwer, R.M., Klein, M., Grasby, K.L., Schnack, H.G., Jahanshad, N., Teeuw, J., Thomopoulos, S.I., Sprooten, E., Franz, C.E., Gogtay, N., Kremen, W.S., Panizzon, M.S., Olde Loohuis, L.M., Whelan, C.D., Aghajani, M., Alloza, Clara, Alnæs, D., Artiges, E., Ayesa-Arriola, R., Barker, G.J., Bastin, M.E., Blok, E., Bøen, E., Breukelaar, I.A., Bright, J.K., Buimer, E.E.L., Bülow, R., Cannon, D.M., Ciufolini, S., Crossley, N.A., Damatac, C.G., Dazzan, P., de Mol, C.L., de Zwarte, S.M.C., Desrivières, S., Díaz-Caneja, C.M., Doan, N.T., Dohm, K., Fröhner, J.H., Goltermann, J., Grigis, A., Grotegerd, D., Han, L.K.M., Harris, M.A., Hartman, C.A., Heany, S.J., Heindel, W., Heslenfeld, D.J., Hohmann, S., Ittermann, B., Jansen, P.R., Janssen, J., Jia, T., Jiang, J., Jockwitz, C., Karali, T., Keeser, D., Koevoets, M.G.J.C., Lenroot, R.K., Malchow, B., Mandl, R.C.W., Medel, V., Meinert, S., Morgan, C.A., Mühleisen, T.W., Nabulsi, L., Opel, N., Ortiz-García de la Foz, V., Overs, B.J., Paillère Martinot, M.-L., Redlich, R., Marques, T.R., Repple, J., Roberts, G., Roshchupkin, G.V., Setiaman, N., Shumskaya, E., Stein, F., Sudre, G., Takahashi, S., Thalamuthu, A., Tordesillas-Gutiérrez, D., van der Lugt, A., van Haren, N.E.M., Wardlaw, J.M., Wen, W., Westeneng, H.-J., Wittfeld, K., Zhu, A.H., Zugman, A., Armstrong, N.J., Bonfiglio, G., Bralten, J., Dalvie, S., Davies, G., Di Forti, M., Ding, L., Donohoe, G., Forstner, A.J., Gonzalez-Peñas, J., Guimaraes, J.P.O.F.T., Homuth, Georg, Hottenga, J.-J., Knol, M.J., Kwok, J.B.J., Le, H.S., Mather, K.A., Milaneschi, Y., Morris, D.W., Nöthen, M.M., Papiol, S., Rietschel, M., Santoro, M.L., Steen, V.M., Stein, J.L., Streit, F., Tankard, R.M., Teumer, A., van‘t Ent, D., van der Meer, D., van Eijk, K.R., Vassos, E., Vázquez-Bourgon, J., Witt, S.H., Brühl, R., Papadopoulos Orfanos, D., Paus, T., Millenet, S., Agartz, I., Ames, D., Amunts, K., Andreassen, O.A., Arango, C., Banaschewski, T., Baune, B.T., Belangero, S.I., Bokde, A.L.W., Boomsma, D.I., Bressan, R.A., Brodaty, H., Buitelaar, J.K., Cahn, W., Caspers, S., Cichon, S., Crespo-Facorro, B., Cox, S.R., Dannlowski, U., Elvsåshagen, T., Espeseth, T., Falkai, P.G., Fisher, S.E., Flor, H., Fullerton, J.M., Garavan, H., Gowland, P.A., Grabe, H.J., Hahn, T., Heinz, A., Hillegers, M., Hoare, J., Hoekstra, P.J., Ikram, M.A., Jackowski, A.P., Jansen, A., Jönsson, E.G., Kahn, R.S., Kircher, T., Korgaonkar, M.S., Krug, A., Lemaitre, H., Malt, U.F., Martinot, J.-L., McDonald, C., Mitchell, P.B., Muetzel, R.L., Murray, R.M., Nees, F., Nenadić, I., Oosterlaan, J., Ophoff, R.A., Pan, P.M., Penninx, B.W.J.H., Poustka, L., Sachdev, P.S., Salum, G.A., Schofield, P.R., Schumann, G., Shaw, P., Sim, K., Smolka, M.N., Stein, D.J., Trollor, J.N., van den Berg, L.H., Veldink, J.H., Walter, H., Westlye, L.T., Whelan, R., White, T., Wright, M.J., Medland, S.E., Franke, B., Thompson, P.M., Hulshoff Pol, H.E.

In this study, we identified common genetic variants that affect rates of brain growth or atrophy in what is, to our knowledge, the first genome-wide association meta-analysis of changes in brain morphology across the lifespan

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